Uterine Fibroid

The uterus is one organ in a complex system that composes the structures common to the internal genitalia of a woman. The uterus is a hollow, pear-shaped organ of reproduction in which the fertilized egg is implanted and the fetus develops. However, the uterus, composed of the cervix, the body and the fundus, can experience stress beyond its role in pregnancy.

One such uterine anomaly is the formation of fibrous or fully developed connective tissue, resulting in abnormal muscle cells, referred to as a uterine fibroid or myoma. A myoma is a benign neoplasm, affecting some 20-30% of all women of age 40 and more than 50% of women overall.

A fibroid forms on the interior muscular wall. Fibroids are spherical, with firm lumps that most often occur in groups. Symptoms of uterine fibroids (and their impact upon general health) include: abnormally heavy menstrual periods, with the likelihood of anaemia; shortened menstrual cycles (less than 28 days); metrorraghia (unexplained uterine bleeding); fatigue; increased vaginal discharge; painful sexual intercourse; and pain or pressure in the bowel or bladder. Yet some women judge their condition to be asymptomatic, with the diagnosis of uterine fibroids being made only after a routine pelvic examination.

Since fibroids tend to increase during pregnancy and decrease during menopause, presumably due to fluctuating levels of estrogen, Uterine fibroids are estrogen-dependent. Three types of estrogen make up the total estrogen load in a female. These include estradiol, estrone and estriol. Both estradiol and estrone are implicated as being carcinogenic under certain circumstances. There is some evidence that estriol is not only noncarcinogenic but also anticarcinogenic as well.

Mother Nature did not leave the female without a defense in regard to downgrading the carcinogenic status of various female hormones. One adaptation is intricately provided by way of hard-working liver. In fact, the liver is the most active metabolic processing center in the body. Among the many vital metabolic functions assigned to the liver,  detoxification or excretion of hormones like estrogen is eardinal. The liver metabolizes estrogen so it can be eliminated from the body by converting it to estrone and eventually to estriol, which has very little ability to stimulate the uterus. If the liver is not effectively metabolizing estradiol, the uterus may become “overestrogenized” and respond with fibroids.

The implications of good liver function are manifold. Most individuals benefit from nutritional support applied to improve liver performance. Noni plays a greater role for improving liver function.

Role of Noni

The flavonoids present in Noni act as antiestrogenic substance that help to prevent the fibroid formation in uterus. Noni act as a great immune enhancer as it contain many immune enhancing phytonutrients. The immune enhancing property of Noni helps in many ways to prevent as well as reducing the fibroid growth in uterus. Noni exhibits antiangiogenesis effects on the malignant cells.

The tumor or fibroid growth has the ability to develop its own blood vessels around to get their nutrition for growth by the process of angiogenesis.  Many phytochemicals present in NONI like Damnacanthal, Alizarin, Limonene, Epigallocatechin gallate (EGCg) etc, just a few among the 150+ phytochemicals present in Noni that exhibit ANTIANGIOGENESIS effect on the fibroid growth and thus inhibits growth and induces program cell death or apoptosis.

Epigallocatechin gallate (EGCg): EGCg is a polyphenolic flavonoids antioxidant found in abundance in Noni. EGCg in Noni inhibits the quinol oxidase (NOX) enzyme tumor activity property thus helps in antiangiogenesis.

Noni ppt : NONI-ppt, the polysaccharide rich substances present in NONI develop an anti-tumor response by stimulating the release of various cytokines mediator of the immune system of our body like :

• Interleukin
•  Interferon – gamma
•  Nitric oxide
•  Tumour necrosis factor
•  Natural killer cells
•  Those immune factors inhibit the growth of tumor or fibroid

Psychological stress : Psychological stress has a profound effect on the functioning of our nervous and endocrine systems. Excess levels of stress will inevitably lead to imbalances of the female reproductive hormones. Although the cause of depression varies greatly from one person to the next, most people with depression have something in common: low levels of neurotransmitter serotonin. Serotonin, also called 5-hydroxytryptamine (5-HT), is the brain’s ‘happy chemical.’ Serotonin is often referred to as the body’s natural mood-altering drug and changes in serotonin levels can quickly alter mood. If serotonin levels drop to low levels, depression is almost sure to follow. It is manufactured in our body using the amino acid tryptophan. When tryptophan is readily available, the body can use it if needed to increase serotonin levels. Manufactured by the body, it is found along with its receptor sites in the brain, blood platelets and lining of the digestive tract. It is also a precursor to a hormone called melatonin, which plays multiple life giving roles in the body, including regulating biological rhythms. The pineal body present in our brain plays an important role in secretion of serotonin and melatonin. NONI helps in correcting the depression symptoms in the following ways

NONI – a safe Way to Increase Serotonin : Noni juice is a normal and safe way for us to increase the effects of this feel good hormone. Whole foods such as NONI juice that elevate serotonin levels naturally, have no side effects. Using precise proportions and relationships to one another, nature combines vitamins, minerals and other phytochemicals and co-factors that make up our food, to enhance benefits of each individual component.

As the hormonal imbalance is one of the causes of uterine fibroid, any body who is using Noni for a long term period shows normal hormonal condition and indirectly it is helping to prevent growth of uterine fibroid.                                       

Recommended Dosage

Divine Noni Concentrate

5ml morning and 5ml evening for 3 days. Then

10ml morning and 10ml evening for next 3 days. Then

15ml morning and 15ml evening for next 8 months.