Toothache

A toothache is generally the result of tooth decay or sometimes an infection. Tooth decay is often caused by poor dental hygiene, although tendency to get tooth decay is partly inherited.

Sometimes, pain in other locations is perceived as occurring in the teeth (this is called referred pain or radiating pain).

Common Causes

•  Tooth decay
•  Abscessed tooth
•  Ear ache
•  Injury to jaw or mouth
•  Heart attack (includes jaw pain, neck pain or toothache)
•  Sinusitis

Role of Noni in Toothache

Noni contains all the vitamins like vitamin A, vitamin B complex, vitamin C, vitamin E. It contains all the trace minerals. A number of major components are identified in Noni plant such as scopoletin, octoanoic acid, potassium, vitamin C, terpenoids, alkaloids, anthraquinones (nordamnacanthal, morindone, rubiadin, and rubiadin-1-methyl ether, anthraquinone glycoside), sitosterol, carotene, vitamin A, flavone glycosides, linoleic acid, Alizarin, amino acids, acubin, L-asperuloside, caproic acid, caprylic acid, ursolic acid, rutin and a putative proxeronine.

Antibacterial activity : Acubin, L-asperuloside and alizarin in Noni fruit, and some other anthraquinone compounds in Noni roots, are all proven antibacterial agents. These compounds fight against infectious bacterial strains like Pseudomonas aeruginosa, Proteus morgaii, Staphylococcus aureus, Baciillus subtilis, Escherichia coli, Salmonella and Shigela. These antibacterial elements within Noni are responsible for treatment of skin infections, colds, fevers and other bacterial-caused health problems.

Cyclo oxygenase (COX) enzyme and its role in inflammation

Pain, redness, heat and swelling which are the markers of inflammation, follow release of prostaglandins. The non-steroidal anti-inflammatory drugs (NSAIDS) reduce prostaglandins by blocking an enzyme which helps to produce them, called cyclooxygenase (COX). There are actually two COX enzymes in the body. They are COX-1 and COX-2. COX-1 is called the good COX enzyme, while COX-2 earned the unflattering name as the bad enzyme. COX1 is easily identifiable and important in regulating cell function. COX2, on the other hand, is generally undetectable in most tissues, but increases to high levels during acute inflammation. The COX2 enzyme is largely responsible for causing pain and inflammation. Injury, disease and trauma cause COX2 enzyme to produce prostaglandins, which cause pain and inflammation. In contrast to the COX-2 enzyme, COX-1 enzyme is responsible for protecting body's stomach lining and kidneys. COX-2 is the key player in inflammation and pain. NSAIDs decrease body's production of both enzymes, thereby decreasing inflammation while at the same time causing harm to the stomach and its lining. The ideal situation would be to find a substance that inhibited only COX-2, but did not significantly affect COX-1.

Noni in pain and inflammatory condition : Noni is a selective COX-2 inhibitor. Researchers found that Noni was a selective inhibitor of COX-2 enzyme. In addition, the Noni did no damage to the COX1 enzyme.

Role of Scopoletin present in Noni in arthritis and inflammation

Another reason for Noni's pain fighting qualities may stem from several of its constituents. Noni  contains Scopoletin, which has anti inflammatory effects. Scopoletin is needed in body for smooth joint movement. It also produces anti-histamine effects.

How Noni works ?

The natural integrity of Noni is only part of the reason for its effectiveness. There are two additional reasons contributing to Noni's effectiveness for a broad range of conditions :

1. Unique Combinations of Substances

2. Synergy of its Substances                   

Recommended Dosage

Divine Noni Concentrate

5ml morning and 5ml evening for 3 days. Then

10ml morning and 10ml evening for next 3 days. Then

15ml morning and 15ml evening for next 8 months.