Thrombocytopenia
Under normal circumstances, the blood contains 150,000 to 350,000 platelets/µL. These platelets are involved in blood clotting. They circulate constantly in the bloodstream, looking for damaged areas. In response to an injury in a blood vessel, the platelets respond by sticking to the site and clumping together (platelet aggregation). This aggregation begins clotting that prevents further bleeding.
Thrombocytopenia occurs when the platelet count falls too low. At levels of 20,000 to 30,000 platelets/µL, bleeding occurs in response to relatively minor trauma. At platelet counts less than 20,000 cells/µL, spontaneous bleeding occurs, which increases risk of bleeding that can result in shock and death.
Like other blood disorders, thrombocytopenia occur when the body either doesn’t produce enough platelets, or if too many platelets are destroyed. Thrombocytopenia is associated with leukemia or lymphoma, aplastic anemia, vitamin B12 or folic acid deficiency anemias, an enlarged spleen, infectious diseases such as HIV/AIDS, and massive blood transfusions.
Two diseases that occur because of increased destruction of platelets are
- Idiopathic thrombocytopenic purpura (ITP)—This disease occurs when antibodies attack and destroy the body’s platelets for unknown reasons. In children, ITP can be an acute condition that occurs after infection.
- Thrombotic thrombocytopenic purpura (TTP)—TTP is a life-threatening disease that occurs when small blood clots form suddenly throughout the body. It results in cardiac hemorrhage and death. It occurs more often in women and is associated with pregnancy, metastatic cancer, chemotherapy, HIV/AIDS and some prescription drugs. Patients with TTP experience kidney failure or decreased kidney function, fever and neurological problems.
Role of Noni
Noni was studied for their ability to promote healthy blood and fight diseases of blood cells, including thrombocytopenia and leukopenia.
Antioxidant vitamins : In a series of animal studies, supplementation with vitamins C, E, and A was investigated to find out effects of these vitamins on thrombocytopenia. Nutritional supplementation with vitamins C, E and A diminished coagulation activation induced by surgery. In this series of studies, use of vitamins C, E and A diminished thrombocytopenia. A fewer deaths occurred after surgery in study animals pretreated with these vitamins. The antioxidant effect of these vitamins diminishes development of free radicals and thereby diminishes platelet cell destruction. Noni contains all vitamins including all antioxidant vitamins. Besides that, it contains lots of phytochemicals that act like effective antioxidants.
Essential Fatty Acids : Noni contains all essential fatty acids. It is associated with prolonged platelet viability, decreased platelet activation (and aggregation) and diminished production of free radicals. Essential fatty acids increase the platelet survivability by decreasing cell loss due to platelet activation.
The extended platelet life span induced by Noni may also be due to reduced generation of free radicals as Noni acts like effective antioxidants.
Immune enhancing property : Noni is a powerful immune booster. It helps in so many obstinate diseases like cancer, AIDS and arthritis by its immune boosting property. Noni enhances production of various immune factors like TNF, macrophages, NK cells etc and thus helps in cancer care. It also contains many ingredients that are having anti carcinogenic properties. As cancer is one of the causes of thrombocytopenia, Noni helps in this case.
Melatonin : A number of studies showed that melatonin enhances blood health by supporting production of blood platelets and neutrophils.
In a pilot study, three patients with ITP were given melatonin up to 46 months. All patients had an initial response after one month of treatment and disease progression subsequently diminished. There were no manifestations of toxicity in any of the study subjects. A follow-up case study of a patient with refractory ITP, which typically has a poor prognosis, showed that melatonin was able to successfully manage the symptoms of severe bleeding. Melatonin has also been shown to enhance the production of platelets and resolve thrombocytopenia in a variety of patients. Noni enhances the production of melatonin by stimulating the pineal body. Noni may be very helpful for thrombocytopenia cases.
In the newest melatonin research, scientists delved into its ability to protect patients with cancer by boosting health of bone marrow, among other benefits. Studies reported that melatonin may decrease thrombocytopenia and neutropenia in patients with cancer. Noni increases the melatonin level in blood in natural way.
Recommended Dosage
Divine Noni Concentrate
5ml morning and 5ml evening for 3 days. Then
10ml morning and 10ml evening for next 3 days. Then
15ml morning and 15ml evening for next 8 months.
