Pelvic Inflammatory Diseases
Pelvic Inflammatory Disease is a general term for infection of the lining of the uterus, the fallopian tubes or the ovaries. The majority of Pelvic Inflammatory Disease cases are caused by the same bacteria that lead to sexually transmitted diseases (such as chlamydia, gonorrhea, mycoplasma, staph, strep). Although the cause of PID most commonly spreads through sex, bacteria may also enter the body after gynecological procedures such as the insertion of an intrauterine device (IUD), childbirth, miscarriage, therapeutic or elective abortion and endometrial biopsy. In the United States, nearly 1 million women develop PID each year. It is estimated that 1 in 8 sexually active adolescent girls will develop PID before reaching age 20. Since PID is frequently underdiagnosed, statistics are probably greatly underestimated.
Risk factors include
- Sexual activity during adolescence
- Multiple sexual partners
- Past history of PID
- Past history of any sexually transmitted disease
- Insertion of an IUD
- Symptoms
The most common symptoms of PID include
- Vaginal discharge with abnormal color, consistency or odor
- Abdominal pain
- Fever (not always present; may come and go)
Other nonspecific symptoms that may be seen with PID include
- Chills
- Irregular menstrual bleeding or spotting
- Increased menstrual cramping
- Menstruation, absent
- Increased pain during ovulation
- Sexual intercourse, painful
- Bleeding after intercourse
- Low back pain
- Fatigue
- Lack of appetite
- Nausea, with or without vomiting
- Frequent urination
- Pain with urination
- Tenderness
Role of Noni
Noni contains all the vitamins like vitamin A , vitamin B complex, vitamin C, vitamin E. It contains all the trace minerals. A number of major components are identified in the Noni plant like scopoletin, octoanoic acid, potassium, vitamin C, terpenoids, alkaloids, anthraquinones (such as nordamnacanthal, morindone, rubiadin, and rubiadin-1-methyl ether, anthraquinone glycoside), sitosterol, carotene, vitamin A, flavone glycosides, linoleic acid, Alizarin, amino acids, acubin, L-asperuloside, caproic acid, caprylic acid, ursolic acid, rutin and a putative proxeronine.
Antibacterial activity : Acubin, L-asperuloside and alizarin in the Noni fruit, and some other anthraquinone compounds in Noni roots, are all proven antibacterial agents. These compounds are shown to fight against infectious bacteria strains likes Pseudomonas aeruginosa, Proteus morgaii, Staphylococcus aureus, Baciillus subtilis, Escherichia coli, Salmonella and Shigela. These antibacterial elements within Noni are responsible for the treatment of skin infections, colds, fevers and other bacterial-caused health problems.
Antioxidant property of Noni
Endogenous antioxidants and role of Noni : Our body has evolved with endogenous defense mechanisms to protect against free radical induced cell damage. Glutathione peroxidase, catalase and Superoxide dismutases are three primary antioxidant enzymes in our body which are involved in direct elimination of free radicals or reactive oxygen species from our body. They require micronutrients like selenium, iron, copper, zinc and manganese as cofactors for their formation and optimum catalytic and effective antioxidant activity. Noni contains all the trace elements that help for optimum catalytic activity of those three important antioxidant enzymes for an effective antioxidant defense mechanism.
Glutathione, ascorbic acid, alpha-tocopherol, beta-carotene, bilirubin, selenium, dihydrolipoic acid, reduced CoQ10, melatonin, uric acid etc., as a whole play a homoeostatic or protective role against ROS produced during normal cellular metabolism and after active oxidation insult. Noni contains all the above phyto chemicals and vitamins in abundant quantity. Glutathione (GSH) is the most significant component which directly quenches Reactive Oxygen Species (ROS) such as lipid peroxides and plays major role in xenobiotic metabolism. Glutathione is a tripeptide made up of the amino acids gamma-glutamic acid, cysteine, and glycine. Noni contains all those glutathione making amino acids in abundant number. Thus Noni increases the body’s glutathione level. Noni stimulates more melatonin secretion from the pineal body. It also maintains ascorbate (vitamin C) and alpha-tocopherol (vitamin E), in their reduced form, which also exert an antioxidant effect by quenching free radicals.
Exogenous antioxidants : Contribution from Noni
A number of other dietary antioxidants known as phytonutrients or phytochemicals that are being increasingly appreciated for their antioxidant activity. One example is flavonoids which are a group of polyphenolic compounds. They are responsible for different brilliant colors like blue, scarlet and orange. Noni contains 150 and above phytochemicals including all flavonoids. Flavonoids exhibit several biological effects such as antitumoural, anti-ischaemic, anti-allergic, anti-hepatotoxic, anti-ulcerative and anti inflammatory activities. These are also known to inhibit the activities of several bad enzymes like lipoxygenase, cyclooxygenase, monooxygenase, xanthine oxidase, glutathione-S transferase, mitochondrial succino-oxidase and protein kinases. Many of the biological activities of flavonoids are attributed to their antioxidant properties and free radical scavenging capabilities. Noni is rich with many flavonoids.
Recommended Dosage
Divine Noni Concentrate
5ml morning and 5ml evening for 3 days. Then
10ml morning and 10ml evening for next 3 days. Then
15ml morning and 15ml evening for next 8 months.
