Hepatic Haemangioma
Hepatic haemangioma are benign tumors of liver that consist of small blood vessels. They are the most common benign tumors of the liver and are present in 7% of healthy people. Hemangiomas are four to six times more common in women than in men. Female hormones promote formation and growth of hemangiomas. Hemangiomas, although referred to as tumors, are not malignant and do not become cancerous.
Hepatic haemangioma and Divine Noni
Divine Noni has the inhibitory activity towards tumour progression and tyrosines kinases receptors:
Tyrosine kinases are enzymes that utilise the amino acid tyrosine for protein synthesis. Many tyrosine kinases like Lck, Src, Lyn and EGF receptors drive tumor cells progression. Those help tumor cells growths and progression. Many phytochemicals like damnacanthal, an anthraquinone compound present in Divine Noni has a potent inhibitory activity towards tyrosine kinases such as Lck, Src, Lyn and EGF receptors. In one study, the effects of damnacanthal on ultraviolet ray-induced apoptosis in ultraviolet-resistant human UVr-1 cells are established. Consequently, the ultraviolet light induced a concurrent increase in both phosphorylated extracellular signal-regulated kinases and stress-activated protein kinases. After pretreatment with damnacanthal, there was stimulatory effect on ultraviolet-induced apoptosis.
Divine Noni exhibits antiangiogenesis effect on tumour
Growth of solid tumors beyond 1-2 mm in diameter requires induction and maintenance of a new blood supply, a process known as angiogenesis. In other way, angiogenesis is the physiological process involving growth of new blood vessels from pre-existing vessels. During its avascular stage, a tumor is small enough to take in nutrients and to expel waste by diffusion. However diffusion is not sufficient to support any continued growth of tumor. This is because the tumor consumes nutrients at a rate proportional to its volume, whereas the supply of nutrients is delivered at a rate proportional to its surface area. The tumor overcomes this deficiency by acquiring a blood supply and it does so by inducing neighboring blood vessels to grow towards the tumor (angiogenesis). Failure to induce an angiogenic response results in tumor ‘dormancy’ and interference with an established blood supply leads to necrosis or apoptosis of tumor cells and tumor regression. Divine Noni exhibits antiangiogenesis effects on tumour cells. Many phytochemicals present in Divine Noni like Damnacanthal, Alizarin, Limonene, Epigallocatechin gallate (EGCg) etc exhibit antiangiogenesis effect on tumor cells.
Immune system boosting character of Divine Noni in Tumour
Divine Noni develops an anti-tumor response by stimulating release of various cytokines mediator of body’s immune system like Interleukin -1beta (IL-1), IL-10, IL-12; Inter feron-gamma (IFN-), Nitric oxide (NO), Tumor necrosis factor (TNF) and Natural killer cells (NK)
Antioxidant property of Divine Noni in tumour
The role of oxidative stress in the genesis of various types of tumors is well established. Several chemical, cell culture and animal studies also indicate that antioxidants may slow or even prevent the development of both benign and cancer tumor. Antioxidant enzymes and vitamins are important group of cellular constituents responsible for maintaining a balance between oxidants and antioxidants within a cell. Among the intracellular antioxidant enzymes, Superoxide-dismutase (SOD) and Glutathione Peroxidase (GPx) are responsible for removal of ROS such as superoxide free radicals and H2O2. On the other hand, vitamin E breaks free radical chain reactions as a result of their ability to transfer a phenolic hydrogen to a peroxy free radical of a peroxidized polyunsaturated fatty acid (PUFA), thereby preventing peroxidation of PUFA contained in cellular and sub-cellular membrane phospholipids. Similarly â-carotene acts as an antioxidant by stabilization of organic peroxide free radicals within its conjugated alkyl structure. Since â-carotene is effective at low oxygen concentrations, it complements the antioxidant properties of vitamin E effective at high oxygen concentration.
Divine Noni contains abundant number of all the antioxidant vitamins like vitamin E, vitamin C, vitamin A, â-carotene, many trace minerals like Zn, selenium, magnesium, phosphorus etc. It also helps to synthesise more antioxidant enzymes such as super oxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) inside your body. It was found that these scavenging enzymes of oxygen free radicals were expressed with great regularity in various tumors. Divine Noni also contains a lot of phytochemicals that are having very effective antioxidant property. Hence it provides a powerful effective antioxidant supplement to the body in case of any type of tumor.
Recommended Dosage
Divine Noni Concentrate
5ml morning and 5ml evening for 3 days. Then
10ml morning and 10ml evening for next 3 days. Then
15ml morning and 15ml evening for next 8 months.
