Endometriosis

Endometriosis is caused by growth of endometrial tissue outside uterus. These collections of endometrial tissue cause lower abdominal pain and infertility and gastrointestinal complications. The cause of endometriosis is unknown. According to the most prevalent theory, endometrial tissue refluxes into the abdominal cavity, where it becomes established. An established colony of endometrial tissue continues to act like normal endometrial tissue even though it is outside the uterus. The tissue responds to normal hormonal fluctuations in a woman’s monthly cycle. During the first part of the cycle, the tissue colony thickens and grows in response to estrogen. In the latter part of the cycle, the tissue degenerates and bleeds, sloughing off the excess cells, causing inflammation and damage to adjacent tissue. Women with endometriosis have elevated levels of inflammatory chemicals, providing a therapeutic target for anti-inflammatory dietary supplements. In about two-thirds of cases, the ovaries are colonized by endometrial tissues. Other common sites for tissue to implant include the fallopian tubes, lining of pelvic cavity, uterine ligaments and the outside lining of uterus, cervix, colon, appendix, and vagina. In severe cases, adhesions of endometrial tissue are found on the vulva, bladder, kidney, arms, legs, lungs, nasal mucosa, spinal column and sites of previous surgical incisions.

One theory that might help explain why some women suffer from endometriosis is the autoimmune theory. According to this theory, macrophages which would normally be expected to destroy the endometrial cells, actually contribute to their colonization. In addition, numbers of T cells and natural killer cells, which are also elements of immune system, are reduced. There is also evidence that the misplaced endometrial cells are resistant to removal by immune cells.

The autoimmune theory of endometriosis is supported by frequent finding of autoantibodies in women with endometriosis and by the high rate of other autoimmune conditions among women with endometriosis, including rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus. Genetics factor also falls to one cause of endometriosis.

An association between endometriosis and exposure to chlorinated hydrocarbons, such as polychlorinated biphenols (PCBs) and dioxin, was demonstrated in laboratory animals; some human data support the association. These toxic chemicals affect hormones and disrupt immune function.

Role of Noni

Supplementation with essential fatty acids reduces the inflammation associated with endometriosis by interfering with production of prostaglandins or cytokines that mediate the pain and many other symptoms seen with endometriosis. Noni contains all essential fatty acids.

Noni has the anti-inflammatory properties. Many ingredients present in Noni like scopoletin, flavonoids, rutin and ursolic acids have anti-inflammatory effects. Hence supplementation of Noni having the potent anti-inflammatory effect helps in endometriosis cases.

According to the autoimmune theory of endometriosis, macrophages, which would normally be expected to destroy endometrial cells, actually contribute to their colonization. In addition, numbers of T cells and natural killer cells, which are also elements of immune system, are reduced. Noni increases production of NK Cells and T that may help in endometriosis

Women with endometriosis are under oxidative stress. Noni has effective antioxidants which contain all antioxidant vitamins like vitamin E, vitamin C, rich with beta-carotenes; many trace elements and lots of phytochemicals. Those phytochemicals have strong antioxidant properties which help to neutralize the damaging effect of free radicals. Noni also helps to synthesize more antioxidant enzymes in our body.

Recommended Dosage

Divine Noni Concentrate

5ml morning and 5ml evening for 3 days. Then

10ml morning and 10ml evening for next 3 days. Then

15ml morning and 15ml evening for next 8 months.