Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is caused by the compression of median nerve, which runs through a small channel in the wrist on palm side. Under normal circumstances, there is very little pressure on the median nerve because the carpal tunnel is inflexible. It is surrounded by bone on three sides and tough ligament on fourth side.
People with CTS experiences numbness, tingling and pain in the first three fingers of the affected hand (or hands).It tends to be more prevalent among women than men. Any activities that involve highly repetitive use of the hands, especially flexion of the fingers, can result in CTS. People at risk include those who use computers, as well as carpenters, grocery checkers, assembly-line workers, meat packers, violinists and pianists and mechanics. Hobbies such as gardening and needlework can sometimes bring on the symptoms, while sports such as rowing, golf, tennis, downhill skiing, archery, competitive shooting and rock climbing also place pressure on the hand and wrist joints. In addition, the syndrome can be caused by underlying disorders that affect the carpal tunnel, including arthritis, thyroid problems, gout, and diabetes.
The nerve compression associated with CTS is due to fibrous bands of tissue that forms inside the carpal tunnel, squeezing the median nerve, although CTS is linked to repetitive stress.
Symptoms and Disease Progression
The early symptoms of CTS typically include tingling or burning in parts of hand that receive in nervation from the median nerve. These include the palm and the palmar sides of the middle three fingers, as well as the palm side of wrist. Pain may also radiate up the arm to the shoulder and sometimes the neck, causing stiffness. These symptoms are caused by an increased volume of tissue in carpal tunnel.
In many cases, patients complain of waking in the middle of the night with pain and a feeling that the whole hand is asleep. Careful investigation usually shows that the little finger is unaffected because the ulnar nerve rather than the median nerve services that finger.
This can be a key piece of information in making the diagnosis. If you awaken with your hand asleep, pinch your little finger to see if it is numb. In advanced stages of CTS, the individual nerve cells making up the median nerve can lose their protective layers of myelin. Disruption of the myelin sheath results in impaired conduction of nerve impulses and eventually leads to damage of axons themselves, producing potentially permanent nerve injury .
Role of Noni
Noni approaches to CTS are based on reducing pressure in the carpal tunnel and relieving pain. Noni contains all the vitamins including vitamin B complex, vitamin B 6,B 1 and B 12 and has a pain-killing effect due to inhibition of body’s natural pain conduction system. Studies showed that vitamin B 6 is effective in relieving the pain associated with CTS, and there is evidence that B 6 deficiency causes CTS.
Noni relieves the inflammation and pain in CTS although people with CTS do not have elevated markers of systemic inflammation, there is no doubt that localized inflammation in the wrist contributes to the condition. There are two enzymes COX-1 and COX-2. COX-1 is called the good COX enzyme, while COX-2 as bad enzyme. COX1 is easily identifiable and is important in regulating cell function. COX2, on the other hand, is generally undetectable in most tissues, but increases to high levels during acute inflammation. The COX2 enzyme is largely responsible for causing pain and inflammation. Noni is a selective COX-2 inhibitor.
There are many ingredients in Noni like scopoletin, rutin, flavonoids, ursolic acids etc and have the anti inflammatory effect.
Recommended Dosage
Divine Noni Concentrate
5ml morning and 5ml evening for 3 days. Then
10ml morning and 10ml evening for next 3 days. Then
15ml morning and 15ml evening for next 8 months.
