Benign Liver Tumor
Tumors are abnormal masses of tissues which form when cells begin to reproduce at an increased rate. The liver grows both non-cancerous (benign) and cancerous (malignant) tumors.
What are non-cancerous liver tumors ?
Non-cancerous (benign) tumors are quite common and usually do not produce symptoms. Often, they are not diagnosed until an ultrasound, computed tomography (CT) scan, or magnetic resonance imaging (MRI) scan is performed. There are several types of benign liver tumors, including the following:
Hepatocellular adenoma
This benign tumor occurs most often in women of childbearing age. Most of these tumors remain undetected. Sometimes, an adenoma ruptures and bleeds into the abdominal cavity, requiring surgery. Adenomas rarely become cancerous.
Hemangioma : This type of benign tumor is a mass of abnormal blood vessels. Up to five % of adults have small liver hemangiomas that causes no symptoms. Treatment is usually not required. Sometimes, infants with large liver hemangiomas require surgery to prevent clotting and heart failure.
Liver tumor and Divine Noni
Divine Noni has inhibitory activity towards tumour progression tyrosines kinases receptors:
Tyrosine kinases are enzymes that utilise the amino acid tyrosine for protein synthesis. Many tyrosine kinases like Lck, Src, Lyn, and EGF receptors drive tumor cells progression. These help tumor cells growth and progression. Many phytochemicals like damnacanthal, an anthraquinone compound present in Divine Noni have a potent inhibitory activity towards tyrosine kinases like Lck, Src, Lyn, and EGF receptors. In one study, the effects of damnacanthal on ultraviolet ray-induced apoptosis in ultraviolet-resistant human UVr-1 cells were established. Consequently, the ultraviolet light induced a concurrent increase in both phosphorylated extracellular signal-regulated kinases and stress-activated protein kinases. After pretreatment with damnacanthal, there was a stimulatory effect on ultraviolet-induced apoptosis.
Divine Noni exhibits antiangiogenesis effect on tumour
Growth of solid tumors beyond 1-2 mm in diameter requires induction and maintenance of a new blood supply, a process known as angiogenesis. In other way, angiogenesis is the physiological process involving growth of new blood vessels from pre-existing vessels. During its vascular stage, a tumor is small enough to take in nutrients and to expel waste by diffusion. Diffusion is not sufficient to support any continued growth of tumor. This is because the tumor consumes nutrients at a rate proportional to its volume whereas supply of nutrients is delivered at a rate proportional to its surface area. The tumor overcomes this deficiency by acquiring a blood supply and it does so by inducing neighboring blood vessels to grow towards the tumor (angiogenesis). Failure to induce an angiogenic response results in tumor 'dormancy' and interference with an established blood supply leads to necrosis or apoptosis of tumor cells and tumor regression. Divine Noni exhibits antiangiogenesis effects on tumour cells. Many phytochemicals present in Divine Noni like Damnacanthal, Alizarin, Limonene, Epigallocatechin gallate (EGCg) etc exhibit antiangiogenesis effect on tumor cells.
Immune system boosting character of Divine Noni in Tumor
Divine Noni develops an anti-tumor response by stimulating release of various cytokines mediator of body's immune system like Interleukin -1beta (IL-1), IL-10, IL-12; Inter feron-gamma (IFN-), Nitric oxide (NO), Tumor necrosis factor (TNF-) and Natural killer cells (NK).
Antioxidant property of Divine Noni in tumor
The role of oxidative stress in the genesis of various types of tumors is well established. Several chemical, cell culture and animal studies also indicate that antioxidants slow or even prevent the development of both benign and cancer tumor. Antioxidant enzymes and vitamins are important group of cellular constituents responsible for maintaining a balance between oxidants and antioxidants within a cell. Among the intracellular antioxidant enzymes, Superoxide-dismutase (SOD) and Glutathione Peroxidase (GPx) are responsible for removal of ROS like superoxide free radicals and H2O2. On the other hand vitamin E breaks free radical chain reactions as a result of their ability to transfer a phenolic hydrogen to a peroxy free radical of a peroxidized polyunsaturated fatty acid (PUFA) thereby preventing peroxidation of PUFA contained in cellular and sub-cellular membrane phospholipids. Similarly â-carotene acts as an antioxidant by the stabilization of organic peroxide free radicals within its conjugated alkyl structure. Since â-carotene is effective at low oxygen concentrations, it complements the antioxidant properties of vitamin E, effective at high oxygen concentration.
Divine Noni contains abundant number of all antioxidant vitamins like vitamin E, vitamin C, vitamin A, â-carotene, many trace elements like Zn, selenium, magnesium and phosphorus. It also helps to synthesis more antioxidant enzymes such as super oxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) inside your body. It was found that these scavenging enzymes of oxygen free radicals were expressed with great regularity in various tumors. Divine Noni also contains lot of phytochemicals that are having very effective antioxidant property. It provides a powerful effective antioxidant supplements to the body in case of any type of tumor.
Recommended Dosage
Divine Noni Concentrate
5ml morning and 5ml evening for 3 days. Then
10ml morning and 10ml evening for next 3 days. Then
15ml morning and 15ml evening for next 8 months.
