Back Ache
Back is an important organ that bears the entire body weight. In the contemporary times, people are leading a very unhealthy lifestyle. Eating habits are poor and physical activity is nil. And the work schedule involves long hours of sitting. It is here where backache problem takes place. Talking about the back pain symptoms, usually the pain is felt in the middle of the back or in the lower back. When the pain aggravates, it spreads to both sides of the waist and hips. When the pain becomes very acute, the patient is recommended bed rest for sometime. Most patients suffer from a problem referred to as cervical and lumbar spondylosis, in which the spine tends to lose its flexibility.
Common causes of backache
- Muscle strain
- Gynaecological problems in women
- Pressure on a nerve root
- Tumors
- Osteoporosis
- Trauma
- Strain in the joints
- Incorrect posture
- Muscular tension
- Faulty living style and inappropriate diet
- Lack of physical fitness exercise
- Kidney problems
- Arthritis
- Wearing of high heel shoes
- Long hours of sitting
Role of Cyclooxygenase (COX) enzyme on pain and inflammation
Pain, redness, heat and swelling which are the markers of inflammation, follow the release of prostaglandins. Aspirin and similar non-steroidal anti-inflammatory drugs (NSAIDS) reduce prostaglandins by blocking an enzyme which helps to produce them, called cyclooxygenase (COX).
There are actually two COX enzymes in the body. They are COX-1 and COX-2. COX-1 is called the good COX enzyme, while COX-2 has earned the unflattering name as the bad enzyme. COX1 is easily identifiable and is important in regulating cell function. COX2 on the other hand, is generally undetectable in most tissues, but increases to high levels during acute inflammation.
The COX2 enzyme is largely responsible for causing pain and inflammation. Injury, disease and trauma cause COX2 enzyme to produce prostaglandins, which cause pain and inflammation. In contrast to the COX-2 enzyme, COX-1 enzyme is responsible for protecting body's stomach lining and kidneys. COX-1 enzymes continually produce protective prostaglandins.
COX-1 is essential for blood clotting and for protecting the stomach. COX-2 is the key player in inflammation, pain and fever. NSAIDs and other arthritis medication decrease the body's production of both enzymes, thereby decreasing pain and inflammation while at the same time causing harm to stomach and its lining. The ideal situation would be to find a substance that inhibited only COX-2, but did not significantly affect COX-1.
Studies in mice demonstrated that Noni has some pain relieving power and sedative activity. Noni is a selective COX-2 inhibitor. There are several other ways in which Noni alleviates the undesirable symptoms of backache.
Researchers at an independent research facility found that indeed Noni was a selective inhibitor of COX-2 enzyme. In addition, the Noni did no damage to the COX1 enzyme. Role of Scopoletin present in Noni in back ache is significant. Another reason for Noni's pain fighting qualities stems from several of its constituents. Noni contains Scopoletin, which has analgesic and anti-inflammatory effects. It also produces anti-histamine effects.
The Noni contains xeronine, all the vitamins, all necessary minerals and 17 amino acids out of 20 and 150+ nutraceuticals which help in providing body's required micronutrients for a smooth and harmonious function of all our system in both health and diseases.
Noni also contains all the trace minerals including calcium and phosphorus. Hence it helps a lot in osteoporosis. Noni acts like an immune modulator.
Recommended Dosage
Divine Noni Concentrate
5ml morning and 5ml evening for 3 days. Then
10ml morning and 10ml evening for next 3 days. Then
15ml morning and 15ml evening for next 8 months.
