Atherosclerosis

Heart attack is the number-one cause of death not only in India but also in whole world. Our fastidious life style, rich diet habits, physical inactivity and stress full mental condition are the predisposing factors of various cardiac problems and heart attacks. The high rise of cholesterol in our blood is one of the causes of many cardiac problems and heart attacks. The oily fatty food, ghee and fried foods have become a habit in our daily routine diet. It causes rise of cholesterol in our blood and plays the main role in generating various heart diseases like coronary artery disease, ischemic heart diseases, atherosclerotic plaques in artery and unstable angina pain.

Cholesterol is of two types – HDL (high density lipoprotein) cholesterol and LDL (low density lipoprotein) cholesterol. Among them HDL cholesterol is good for our body. But LDL cholesterol is named as bad cholesterol and this is the one which is the route cause of coronary artery diseases, angina pain, and atherosclerosis of artery. But LDL cholesterol is not really bad in its native form because God did not make a mistake when he created it. Native LDL cholesterol is good. In fact, it is essential for building good cell membrane, other cell parts and many different hormones that our body needs. Problems begin when native LDL cholesterols are oxidized by free radicals in our body and make them harmful cholesterol. The high environmental pollutions, our stressful life style and good nutrients depleted diet are the main causes of over production of free radicals in our body. Those free radicals play the main role to oxidize LDL cholesterol and make it harmful to our body.

The inner layer of our artery is called the endothelium which is an extremely sensitive lining vulnerable to even the slightest irritation. Oxidized cholesterol and excessive free radicals cause the oxidative stress that injures the endothelium. Our body has a defense system designed to protect this endothelium of the artery. In the events of injury, our body respondes by sending WBC (mainly monocytes) to eliminate the harmful oxidized LDL cholesterol. Here the defense team of monocytes starts gobbling up the enemy to minimize irritation to endothelium. If this response process is successful, the problem is over and lining of artery will be repaired. But this is not what usually happens. Monocytes continue to gather delinquent oxidized LDL cholesterol, but they do not let any out. The monocytes get crammed so full of oxidized LDL cholesterol(fat) that it becomes a foam cell, looks like a ball of fat. This foam cells then attach itself to the lining of the artery and eventually forms the initial defect of hardening of arteries which is called fatty streak. The fatty streak is an inflammatory lesion. This leads to form a plaque. It is the initial step in the process called atherosclerosis. The atherosclerotic plaque goes on increasing in size and consequently makes the artery narrow inside to pass blood flow. The entire process is a vicious cycle. Not only there is build up plaque, but there is also thickening of artery. Normally the layer of endothelium functions well by releasing an important product called nitric oxide (NO). During this inflammatory response, the appropriate release of nitric oxide is blocked from the endothelium, causing endothelium to function poorly. This in turn causes platelets of blood to adhere to plaque and artery around plaque to go into spasm. About 50% of heart attacks are the rapture of one of these plaques and the clot that forms around a ruptured plaque. A situation such as this causes acute and abrupt total closure of this artery, which blocks the blood flow to that part of the heart. Oxidative stress also causes break down of these plaques, which eventually leads to their rupture.

Arteries keep narrowing to the point that they become occluded. These patients usually have symptoms of chest pain that is called unstable angina.

So to neutralize the notorious activity of these free radicals to convert the native LDL cholesterol to harmful LDL cholesterol, some powerful antioxidants are required. These antioxidants not only neutralize effect of free radicals on vessel cells but also to other cells. DIVINE NONI JUICE IS HIGH IN ANTIOXIDANTS.

NONI has the powerful antioxidant properties that help to neutralize free radicals role of oxidation of the native LDL cholesterol to harmful LDL cholesterol and thus protects the arterial endothelial lining from injury and future developing atheromatous plaque. The main antioxidants are vitamins A, E and C, beta-carotene, glutathione, bioflavonoid, selenium, zinc, CoQ10 (ubiquinone) and various phyto-chemicals. NONI is rich in Vit A, Beta carotene, Vit E, C, glutathione, bioflavonoid, selenium, zinc and many more essential phytochemicals. Melatonin, a hormone produced by the pineal gland, is also a potent antioxidant. NONI stimulates more melatonin release from pineal gland.

Why Noni works as powerful antioxidant : There are two reasons :

1. Unique Combinations of Substances

Noni has an impressive combination of ingredients.

2. Synergy of its Substances

Noni and nitric oxide – its role in preventing arterial cells damage

Normally, the layer of endothelium functions well by releasing an important product called nitrous oxide (NO). During this inflammatory response of forming the plaques, however, the appropriate release of nitric oxide is blocked from endothelium, causing endothelium to function poorly. NONI helps proper production of nitrous oxide in our body and thus helps the endothelium to function smoothly.

Noni promotes the cellular growth

In addition to the antioxidant activity in Noni, Dr. Ralph Heinicke, pinpointed one constituent in Noni that he believes, is responsible for the Juice’s ability to promote cellular growth. These are parts of his postulated xeronine system, which consists of proxeronine, proxeroninase, and xeronine.

The xeronine theory, which is based on Dr. Heinicke’s work, postulates that once in the body, proxeronine travels to specific parts of cells, like mitochondria, microsomes, Golgi apparatus, reticuloendothelium and electron transport system. Within the cell, these components communicate with each other (intracellular) and with other cells (intercellular). Thus xeronine maintains cellular growth of vessels wall and plays an important role in prevention of atherosclerotic condition.

Recommended Dosage

Divine Noni Concentrate

5ml morning and 5ml evening for 3 days. Then

10ml morning and 10ml evening for next 3 days. Then

15ml morning and 15ml evening for next 8 months.